Ultimate Guide: 4 Tips for How to Use Baicalin (baikal skullcap herb)

Baicalin, the active compound from the Blue baikal Skullcap herb, has many health benefits. People are using more and more Baicalin, but many people still wonder how to use Baicalin correctly. In this post, we’ll go into detail about how to use baicalin extract powder.

Baicalin is a great supplement for anybody looking to improve their health, or as an addition to a health stack. It’s also great for reducing stress and helping to promote healthy sleep cycles. Please read on for more information about the correct way to use baicalin for optimal health benefits.

baicalin promotes better health
Baicalin promotes good health!

1. Top Baicalin (baikal skullcap) uses – SO many!

Baicalin is used for a number of great effects. We’ll briefly summarize some of the best uses for baicalin right here. People use baicalin for a number of health benefits. These include, but are not limited to:

  • Strong antioxidant effects[1]
  • Promoting healthy sleep[2]
  • Reducing inflammation[3]
  • Promotion of relaxation and pain relief[4]
  • Stress reduction[5]
  • Skin protection[6]


As you can see, Baicalin is somewhat of a ‘super-supplement’. Its multiple benefits have all been scientifically verified (see our references).[7] [8] It’s no wonder the ancient Chinese healers treated the Blue Skullcap with such reverence!


2. Optimal powder dosage

Scientists and users are still unsure of the correct and optimal dosage of baikal skullcap herb for humans. There is still a need for funding for human studies to discover the optimal Baicalin powder dosage. However, based on previous animal studies, it seems the best Baicalin dosage is around 500 mg of root extract.[9]


3. Solubility

Baicalin extract is great because of how soluble it is! [10] This means that you can easily dissolve your baicalin dietary supplement into a glass of water or juice in the morning, to kick-start your day.

You can also add Baicalin powder to smoothies, health drinks, or simply take the powder on its own or in a capsule.


4. Side Effects

Baicalin has been used for nearly a thousand years in ancient Chinese traditional medicine. The use of baicalin as a dietary health supplement is very safe. However, there have been few studies about safety in pregnant women and people with underlying medical conditions.

Baicalin interacts with GABA-A subtype receptors so please use with caution if taking benzodiazepines, alcohol, or antidepressants as baicalin may interfere with these.



In conclusion, baicalin is a powerful compound with a great number of health benefits. The correct dosage for baicalin depends on the strength of your supplement. We recommend taking root extracts at doses of around 500 mg daily. If you’re taking a stronger product, rather start with a lower dose of around 200 mg, and see how you respond.

Baicalin powder is highly soluble and can be dissolved in water or juice. It can also be added to healthy smoothies, or simply taken as is.

baicalin skullcap



[1] Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin, DE Shieh et al., Anticancer Res. 2000 Sep-Oct;20(5A):2861-5

[2] Biphasic effects of baicalin, an active constituent of Scutellaria baicalensis Georgi, in the spontaneous sleep-wake regulation, HH Chang et al., J Ethnopharmacol. 2011 May 17;135(2):359-68. doi: 10.1016

[3] Baicalin attenuates inflammation by inhibiting NF-kappaB activation in cigarette smoke induced inflammatory models, Z Lixuan et al., Pulm Pharmacol Ther. 2010 Oct;23(5):411-9. doi: 10.1016

[4] The anti-inflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia, TC Chou et al., Anesth Analg. 2003 Dec;97(6):1724-9

[5] Anxiolytic-Like Effect of baicalin and its additivity with other anxiolytics, Xu Z et al., Planta Med. 2006 Feb;72(2):189-92

[6] Effects of baicalin against UVA-induced photoaging in skin fibroblasts, W Min et al., Am J Chin Med. 2014;42(3):709-27. doi: 10.1142

[7] Baicalin, a flavonoid, affects the activity of human dermal papilla cells and promotes anagen induction in mice, SH Shin et al., Naunyn Schmiedebergs Arch Pharmacol. 2015 May;388(5):583-6. doi: 10.1007

[8] Baicalin, a metabolite of baicalein with antiviral activity against dengue virus, E Moghaddam et al., Sci Rep. 2014; 4: 5452, Published online 2014 Jun 26. doi: 10.1038/srep05452

[9] Scutellaria baicalensis, Examine.com, available from https://examine.com/supplements/scutellaria-baicalensis/, retrieved on August 17, 2016

[10] Baicalin (CAS 21967-41-9), Santa Cruz Biotechnology, available from http://www.scbt.com/datasheet-204638-baicalin.html, retrieved on August 17, 2016